rvical cancer, after breast cancer, is one of the most common cancers among women and is recognized as a serious and challenging disease. Like other types of cancer, it can appear as either benign or malignant and originates from the abnormal proliferation of cervical cells. However, adhering to prevention principles, including regular check-ups, practicing safe sex, and timely Pap smear tests, can play a significant role in reducing the risk of developing this disease.
What is the uterus and what role does it play in women’s health?
The uterus is one of the most important organs of the female reproductive system and serves as the main site for the growth and development of the fetus. This internal organ has a muscular and flexible structure that allows it to change size and expand during pregnancy. The uterus consists of two main parts: the upper part, which includes the fundus, fallopian tubes, ovaries, and ligaments, playing a crucial role in ovulation and fertilization, and the lower part, which includes the body of the uterus, isthmus, cervix, and vagina, directly involved in childbirth and the expulsion of the fetus. Better understanding of the structure and function of the uterus can help maintain women’s health and prevent some related diseases.
Understanding the Structure of the Uterus and Its Various Parts
The uterus is one of the key organs in the female reproductive system, consisting of two main parts: the upper section and the lower section. Each of these parts contains essential components that play a role in fertility, pregnancy, and childbirth. Below, we will explore each of these sections and their functions in more detail.
Lower Section and Its Components
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Cervix: The lowest part of the uterus, located between the uterus and the vagina. This muscular and fibrous structure has a protective role and is important during menstruation and childbirth. The cervix dilates during labor to help expel the baby.
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Body of the Uterus (Corpus): This part of the uterus begins beneath the fallopian tubes and extends downward. As it moves toward the lower part of the uterus, it narrows and reaches the isthmus. The body of the uterus is where the embryo implants and grows during pregnancy.
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Isthmus: This narrow section is located between the body and cervix and plays a significant role in the structural changes of the uterus, especially during pregnancy.
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Vagina: One of the most important parts of the lower uterus, it directly connects with reproductive functions. The vagina not only plays a role in sexual intercourse but also facilitates menstrual blood flow and the expulsion of the baby during childbirth. Its muscular and flexible structure allows it to adapt in size under different conditions.
Upper Section and Its Components
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Fundus: The highest part of the uterus, dome-shaped, and located above where the fallopian tubes connect. The fundus plays an essential role in supporting the growth and maintenance of the fetus during pregnancy.
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Fallopian Tubes: These narrow structures are responsible for transporting eggs from the ovaries to the uterus. Sperm also combines with the egg in this section, where fertilization occurs.
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Ligaments: A collection of supportive tissues that hold the uterus in place and support other reproductive organs within the pelvic cavity.
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Ovaries: Two oval-shaped glands located on either side of the uterus, responsible for producing eggs and secreting female hormones, including estrogen and progesterone.
The lower section of the uterus is particularly important because it plays a central role in pregnancy, childbirth, and women’s reproductive health. The cervix and vagina are directly involved in childbirth and reproductive functions, and a closer examination of them helps in better understanding women’s fertility health.
What is cervical cancer and how does it develop?
Cervical cancer is one of the most common types of cancer in women, originating from the tissue of the cervix. This disease occurs when the normal cells in this area undergo abnormal changes and transform into precancerous or cancerous cells. However, not all precancerous cells lead to cancer; if these cells grow uncontrollably, they may eventually lead to cervical cancer. Timely detection of these changes through regular tests such as the Pap smear plays an important role in preventing and early diagnosis of this disease.
Understanding the types of cervical cancer
Cervical cancer is divided into two main types, each with different characteristics and incidence rates:
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Squamous Cell Carcinoma: This is the most common form of cervical cancer, accounting for about 80 to 90 percent of cases. It originates from the thin, flat cells that cover the surface of the cervix and is usually caused by long-term infections with the Human Papillomavirus (HPV).
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Adenocarcinoma: This type is less common, making up 10 to 20 percent of cervical cancers. It originates from glandular cells that produce mucus in the cervix, and its incidence has increased in recent years.
Stages of cervical cancer
Cervical cancer progresses through four stages:
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Stage 1: In this stage, the cancer is confined to the cervix and has not spread to surrounding tissues.
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Stage 2: The cancer has spread beyond the cervix and may have reached the upper part of the vagina or tissues near the uterus.
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Stage 3: In this stage, the cancer has spread to the pelvic area, lymph nodes, and surrounding tissues.
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Stage 4: The most advanced stage, in which cancer cells have spread to organs such as the liver, bladder, intestines, and other parts of the body.
What causes cervical cancer?
One of the main causes of cervical cancer is infection with the Human Papillomavirus (HPV). This virus, which is primarily transmitted through sexual contact, has over 100 different types, but two types, HPV-16 and HPV-18, play the most significant role in causing cancer.
Interestingly, HPV is also the primary cause of genital warts, in addition to cervical cancer. However, not all types of this virus are cancer-causing, and HPV vaccination, along with maintaining good hygiene, can significantly reduce the risk of infection.
Read more: Breast cancer screening | Best age for screening
Who is at greater risk for cervical cancer?
Certain conditions and factors can increase the risk of cervical cancer. These factors include hormonal changes and specific health conditions that may disrupt cell growth. Individuals who are at higher risk include:
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Diabetes: People with diabetes have a weaker immune system, which can reduce the body’s resistance to viral infections like HPV.
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Obesity: Obesity, especially in the abdominal area, can increase estrogen production, which is a trigger for cancer development.
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High blood pressure: High blood pressure, as a risk factor for other health problems, can lead to hormonal imbalances and damage to various tissues in the body.
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Genetics and family history: If there is a family history of cervical cancer, the risk of developing the disease increases.
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Use of certain medications: Medications like tamoxifen, which are used to treat breast cancer, can increase the risk of cervical cancer.
Cervical cancer and genetics
In some cases, this disease may have a genetic root. Individuals with a family history of cervical cancer are at a higher risk of developing the disease.
Symptoms of Cervical Cancer
Cervical cancer typically does not show noticeable symptoms in its early stages, making it difficult to detect until it has advanced. When symptoms do appear, they may be mistaken for common period-related symptoms. Some of the most common symptoms of cervical cancer include:
- Excessive fatigue
- Abdominal and pelvic pain
- Unexplained weight loss and loss of appetite
- Pain during urination
- Abnormal vaginal discharge with changes in color and odor
- Irregular vaginal bleeding, especially between periods, after sexual intercourse, or after menopause
- Back pain and swelling in the legs
- Frequent need to urinate
If you experience any of these symptoms, it is crucial to consult a healthcare provider and schedule an examination.
Is Cervical Cancer Fatal?
Cervical cancer is treatable and preventable if detected early. Early treatment can prevent the disease from progressing and can save lives. However, if untreated, cervical cancer can spread to other parts of the body and cause serious health problems and a decreased quality of life. Early diagnosis and preventive measures are critical in reducing the risk and mortality from this disease.
Age of Onset for Cervical Cancer
Cervical cancer is most commonly diagnosed in women aged 35 to 44 years. However, statistics show that about 15% of those diagnosed are over 65 years old. Interestingly, cervical cancer can even occur in virgins who have never had vaginal intercourse.
While the primary risk factor for this cancer is sexually transmitted infections such as the human papillomavirus (HPV), the disease can also arise due to other factors. Therefore, not engaging in vaginal intercourse may reduce the risk, but it does not eliminate it completely.
When to See a Doctor
If you experience symptoms of cervical cancer, especially if they occur frequently or are severe, it is essential to see a gynecologist as soon as possible. Symptoms to watch out for include:
- Unusual bleeding, particularly during menopause, between periods, or after intercourse
- Unexplained vaginal or abdominal pain that is frequent
- Unexplained weight loss
- Pelvic pain
When to See a Doctor
If you experience symptoms of cervical cancer, especially if they occur frequently or are severe, it is essential to visit a gynecologist as soon as possible. Symptoms to watch out for include:
- Abnormal bleeding, especially during menopause, between periods, or after sexual intercourse
- Unexplained vaginal or abdominal pain that is frequent
- Unexplained weight loss
- Pelvic pain
These symptoms may be confused with other conditions, so consulting a specialist for an accurate diagnosis is crucial.
For More Information: Read here about everything you need to know about oncology | Best Oncology Clinic in Golestan.
Diagnosis of Cervical Cancer
To make an accurate diagnosis, it is essential to visit the best cancer diagnosis and treatment clinic in Gorgan. The diagnosis of cervical cancer typically involves examining symptoms and performing certain specialized tests. These tests include:
- Pelvic and vaginal examination
- Pap smear test: This test collects a sample of cells from the cervix to check for any potential changes.
- Transvaginal ultrasound: This ultrasound provides a clear image of the uterus.
- Hysteroscopy: This procedure allows doctors to examine the inside of the uterus and check for any issues.
Cervical Cancer Testing
The Pap smear test is one of the most common tests for detecting cervical cancer. Women should undergo this test regularly:
- Women aged 21 to 29: Every 3 years
- Women aged 30 to 65: In addition to the Pap test, HPV testing should also be done every 5 years.
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